NGS Panels
Choose the panel that corresponds to the pathology you want to test your patient for
TAT (turnaround time): 4 weeks
Hereditary cancer and Genetic syndromes with predisposition to cancer Global panel [128 genes]
Gene list:
A2ML1, ACD, APC, AKT1, ATM, ATR, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRAF, BRCA1, BRCA2, BRIP1, BUB1B, CBL, CCDC73, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, CHEK2, CREBBP, DICER1, EPCAM, EP300, EGLN1/PHD2, EPAS1, EYA4, EZH2, KIF1B, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FANCP (SLX4), FANCQ (ERCC4), FANCR (RAD51), FANCT (UBE2T), FANCU (XRCC2), KRAS, KLLN, MAD2L2 (FANCV, REV7), FANCW (RFWD3), FH, FLCN, GNAS, GREM1, HOXB13, HRAS, LZTR1, MAP2K1, MAP2K2, MAP3K8, MYST4 (KAT6B), MAX, MEN1, MET, MITF, MLH1, MRE11A, MSH2, MSH6, MUTYH, NBN, NF1, NF2, NKX2-1 (TTF-1), NRAS, NSD1, NTHL1, PALB2, PMS2, PIK3CA, POLE, POLD1, POT1, PRKAR1A, PTCH1, PTEN, PTPN11, PRSS1, SPINK1, RAD51C, RAD51D, RAF1, RASA1, RASA2, RIT1, RRAS, RB1, RET, RMI2, SDHA, SDHAF2, SDHB, SDHC, SDHD, SEC23B, SETBP1, SHOC2, SMAD4, SMARCB1, SMARCA4, SMARCE1, SOS1, SOS2, SPRED1, SPRY1, STK11, SUFU, SYNGAP1, TMEM127, TERT, TERF2IP, TP53, TSC1, TSC2, VHL, WRN, WT1.
Breast cancer extended panel [12 genes]
Gene list:
ATM, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, PALB2, PTEN, TP53, STK11, NBN, NF1.
Ovarian cancer panel [12 genes]
Gene list:
BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PMS2, RAD51C, RAD51D, STK11, DICER.
Prostate cancer panel [12 genes]
Gene list:
ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, NBN, PMS2, TP53.
Pancreatic cancer panel [17 genes]
Gene list:
APC, ATM, BRCA1, BRCA2, CDKN2A, CDK4, EPCAM, FANCC, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, TP53, PRSS1, SPINK1.
Diffuse gastric cancer and gastrointestinal stromal tumor panel [6 genes]
Gene list:
CDH1, CDKN1B, SDHA, SDHB, SDHC, SDHD.
Colorectal cancer and polyposis panel [11 genes]
Gene list:
AXIN2, APC, BMPR1A, MUTYH, NTHL1, SMAD4, PTEN, POLE, POLD1, STK11, GREM1.
Lynch syndrome panel [5 genes]
Gene list:
EPCAM, MLH1, MSH2, MSH6, PMS2.
Gastrontestinal / Colorectal cancer panel [24 genes]
Gene list:
AXIN2, APC, BMPR1A, CDKN1B, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, PMS2, MUTYH, NTHL1, SMAD4, SDHA, SDHB, SDHC, SDHD, TP53, PTEN, POLE, POLD1, STK11, GREM1.
Renal cancer panel [17 genes]
Gene list:
BAP1, CDC73, EPCAM, FH, FLCN, MET, MITF (p. E318K), PTEN, SDHA, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, VHL, WT1.
Melanoma panel [11 genes]
Gene list:
ACD, BAP1, BRCA2, CDKN2A (p.16), CDK4, TP53, MITF (p. E318K), PTEN, POT1, TERT, TERF2IP.
Thyroid medullary carcinoma and multiple endocrine neoplasia panel [3 genes]
Gene list:
MEN1, RET, CDKN1B
Pheochromocytoma / Paraganglioma panel [17 genes]
Gene list:
CDKN1B, FH, MAX, MEN1, NF1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, VHL, EGLN1/PHD2, EPAS1, KIF1B, MET.
Medulloblastoma and other tumors of the central nervous system panel [19 genes]
Gene list:
APC, BRCA2, CREBBP, DICER1, EP300, NF1, NF2, PALB2, PTCH1, PTEN, SUFU, TP53, RB1, SMARCB1, SMARCA4, SMARCE1, TSC1, TSC2, VHL.
RASopathies panel [25 genes]
Gene list:
A2ML1, BRAF, CBL, EYA4, KRAS, HRAS, LZTR1, MAP2K1, MAP2K2, MAP3K8, MYST4 (KAT6B), NF1, NRAS, RAF1, PTPN11, RASA1, RASA2, RIT1, RRAS, SHOC2, SPRED1, SOS1, SOS2, SYNGAP1, SPRY1.
Fanconi anemia panel [22 genes]
Gene list:
FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCJ (BRIP1), FANCI, FANCL, FANCM, FANCN (PALB2), FANCO (RAD51C), FANCP (SLX4), FANCQ (ERCC4), FANCR (RAD51), FANCS (BRCA1), FANCT (UBE2T), FANCU (XRCC2), MAD2L2 (FANCV, REV7), FANCW (RFWD3).